If you are using E1000 adapters in your virtual machines, you should take a look at KB 2059053.
If the operating system is using RSS (Receive Side Scaling, practically all operating systems since Vista are using it) it is possible that your ESXi 5.0/5.1/5.5 host will die with a PSOD (Purple Screen of Death) with errors containing E1000PollRxRing and E1000DevRx.
Update 30.01.2014 for ESX 5.1: A patch is available: see KB2062300 for more information / Patch from KB 2062300 is included in ESXi 5.1 Update 2
Update 24.11.2015 for ESX 5.5: Issue is fixed in VMware ESXi 5.5, Patch Release ESXi550-201410001 (2087358) For more information, see VMware ESXi 5.5, Patch Release ESXi550-201410001 (2087358).
Workaround: workaround is to use the VMXNET3 adapters instead of the E1000.
The other possibility would be to disable RSS within the windows virtual machine – but I would prefer the change to the VMXNET3…
If you really want to disable RSS in your Win2008 (or newer) Server operating System you can use this command:
netsh int tcp